Hydroxamic Acids: A Unique Family of Chemicals with Multiple Biological Activities
Satya P. Gupta's Hydroxamics Acids is the first book to compile invited articles written by international experts on the class of compounds hydroxamic acids. Found to possess a wide spectrum of biological activities, the hydroxamic acids are of interest to theoretical and experimental chemists who can study and make use of them in drug design and development. Chapters in this book provide a diverse and comprehensive coverage of this compound class and consequently this publication is a valuable resource for researchers in chemical, pharmaceutical and biological sciences.
Mitä ihmiset sanovat - Kirjoita arvostelu
Yhtään arvostelua ei löytynyt.
2 Theoretical Studies on Hydroxamic Acids
3 Hydroxamates as Carbonic Anhydrase Inhibitors
4 StructureActivity Relationship Studies of Hydroxamic Acids as Matrix Metalloproteinase Inhibitors
5 Hydroxamic Acids as Histone Deacetylase Inhibitors
6 Hydroxamates as Ribonucleotide Reductase Inhibitors
7 Hydroxamic Acid Derivatives as Potential Anticancer Agents
8 Quantitative StructureActivity Relationship Studies on Hydroxamic Acids Acting as Histone Deacetylase Inhibitors
9 Hydroxamic Acids as Inhibitors of Urease in the Treatment of Helicobacter pylori Infections
10 Therapeutic Potential of Hydroxamic Acids for Microbial Diseases
11 Hydroxamic Acids as Chelating Mineral Collectors
Muita painoksia - Näytä kaikki
Hydroxamic Acids: A Unique Family of Chemicals with Multiple Biological ...
Satya P. Gupta
Esikatselu ei käytettävissä - 2016
3D-QSAR acetohydroxamic acid acetylation amino acid analogues anion anticancer agents antiproliferative activity antitumor activity apoptosis atom Biol biological Bioorg Med Chem cancer cell carbonic anhydrase carboxylic cell lines chelating Chem Chem Lett Chen clinical collectors CoMFA complexes compounds CoMSIA coordination crystal structure Curr deprotonation didox diseases drug design enzyme flotation Gupta HDAC inhibitors HDAC6 HDAC8 Helicobacter pylori histone deacetylase inhibitors human hydrogen bonding hydrophobic hydroxamic acid derivatives Hydroxyurea IC50 values infection inhibition inhibitory activity Inorg interactions ligand LpxC marimastat matrix metalloproteinase matrix metalloproteinase inhibitors metal ions mineral MMP inhibitors MMPIs MMPs moiety molecular molecules NHOH novel oxygen pharmacophore phase potent protein proton QSAR Quantitative structure-activity relationship residues ribonucleotide reductase role SAHA Scozzafava selective siderophores steric structure-activity relationship substituent sulfonamide Supuran synthesis TACE target tautomer trichostatin tumor urease vitro vivo Wang Zhang zinc