Isoflavones: Chemistry, Analysis, Function and EffectsVictor R. Preedy Royal Society of Chemistry, 2013 - 683 sivua Isoflavones remain the subject of many scientific studies most of which reveal them to have some health benefits. Coverage within this book begins with an overview of phytoestrogens in health and plants with specific reference to isoflavones, how isoflavones are found in the diet and novel compounds in nuts. Expert accounts of the chemical and biochemical research on this topic are provided followed by analytical and bioanalytical assessments. Rounding up the book are the chapters on function and effects of isoflavones which provide details on isoflavones in beverages, soy and soy products and other food delivery systems and how their function effects the thyroid, menopause, prostate, breast, bone and cardiovascular disease to name but a few. Delivering high quality information, this extensive and detailed book provides a fascinating insight into this area of health and nutritional science. It will bridge scientific disciplines so that the information is more meaningful and applicable to health in general. Part of a series of books, it is specifically designed for chemists, analytical scientists, forensic scientists, food scientists, dieticians and health care workers, nutritionists, toxicologists and research academics. Due to its interdisciplinary nature it could also be suitable for lecturers and teachers in food and nutritional sciences and as a college or university library reference guide. |
Sisältö
Chapter | 3 |
Chapter | 12 |
Summary Points | 23 |
Isoflavones in Foods and Ingestion in the Diet | 28 |
The ChemistryBiochemistry of the Bioconversion | 49 |
Chemistry and Synthesis of Daidzein and its Methylated | 61 |
Summary Points | 78 |
The Structure of Isoflavones by 1D and 2D Homonuclear | 94 |
Summary Points | 326 |
Analysis of Novel Isoflavone Digycoside in Nuts | 333 |
Implications | 349 |
Isoflavones in Beverages | 365 |
Optimizing Isoflavonerich Food Delivery Systems | 399 |
Summary Points | 417 |
An Overview | 423 |
Function and Effects | 438 |
Chapter 13 | 106 |
a Comparison | 115 |
The Biological Effects of Genistein and its Intracellular | 131 |
Genistein Chemistry and Biochemistry | 148 |
When Plants | 157 |
Isoflavonoids | 167 |
Analysis | 176 |
Summary Points | 190 |
Highperformance Liquid Chromatographic | 196 |
Highthroughput Quantification of Pharmacologically Active | 218 |
14 | 238 |
Food and Nutritional Components in Focus No 5 | 244 |
Summary Points | 274 |
LCMSMS Profiling of Isoflavone Glycosides | 280 |
Puerariae radix Isoflavones | 294 |
Pattern Profiling and Quantitative Determination | 316 |
Dietary Isoflavones and Learning and Memory | 451 |
Glycitein in Health | 465 |
Isoflavones and Prenatal Exposure to Equol | 480 |
GABAA and NMDA Receptors | 500 |
Summary Points | 512 |
Estrogenic Activity and Molecular Mechanisms | 518 |
Genistein and Insulin Secretory Function | 529 |
Summary Points | 537 |
Soy Isoflavones and Testicular Function | 562 |
Equol and Cell Proliferation | 580 |
Bone Genistein Daidzein and Equol | 597 |
Summary Points | 606 |
Isoflavones for Menopausal Vasomotor Syndrome | 627 |
646 | |
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acid activity adipocytes Adlercreutz aglycones Agricultural and Food analysis antioxidant apoptosis binding bioavailability biochanin biological biotransformation breast cancer cancer cells chemical Chen Clinical compounds concentrations conjugates coumestrol daidzein daidzein and genistein diet dietary isoflavones effects of genistein enzymes equol ER-b estrogen receptor extraction fermented Figure flavones flavonoids Food Chemistry formononetin function GABAA receptors genistein genistein and daidzein glucuronide glycitein glycosides HMBC hormone HPLC HSQC human hydrolysis hydroxyl hydroxyl group increased inhibition insulin intake interaction intestinal isoflavone content isoflavones isoflavonoids Journal of Agricultural Journal of Nutrition Key Facts kinase levels liquid chromatography malonyl menopausal metabolism metabolites method microwave molecular molecules NMDA OCH3 oxidative pathway phytoestrogens plant plasma postmenopausal prostate protein protons puerarin rats ring sample Setchell Society of Chemistry solvent soybean soymilk spectra structure studies sulfate synthase synthesis temperature THIF thyroid tissue tofu total isoflavone vitro Wang xenoestrogens