The Organic Chemistry of Biological Pathways

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Roberts and Company Publishers, 2005 - 490 sivua
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Intended for advanced undergraduates and graduate students in all areas of biochemistry, The Organic Chemistry of Biological Pathways provides an accurate treatment of the major biochemical pathways from the perspective of mechanistic organic chemistry.

 

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Sisältö

Common Mechanisms in Biological Chemistry 1
11
Common Mechanisms in Biological Chemistry 1
18
Problems
37
Biomolecules
43
Lipid Metabolism
93
Carbohydrate Metabolism
161
Amino Acid Metabolism
221
Nucleotide Metabolism
305
References
332
Biosynthesis of Some Natural Products
339
A Summary of Biological Transformations
409
Appendixes
429
B Using the KEGG and BRENDA Databases
436
Abbreviations Used in This Book
474
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The Organic Chemistry of Biological Pathways, Second Edition
John McMurry,Tadhg Begley
Esikatselu ei käytettävissä - 2015

Yleiset termit ja lausekkeet

3-phosphate 5-Phospho acetyl CoA active addition reaction alcohol amino acids aspartate atom base begins biological biosynthesis bond carbon carbonyl group catabolism catalyzed CH2OH CH₂OPO32 CH3 CH3 CH3 H CH3O CO₂ CO₂ CO₂ H CO₂H coenzyme complex compounds conversion cycle cysteine decarboxylation deprotonated diphosphate double bond electron enolate enzyme example Fe(II final followed formation fructose give glucose Glutamate glyceraldehyde 3-phosphate H CH3 H H H H H3C H NH3 H₂N H₂O H3C CH3 H3C H H3C H3C hydrogen hydrolysis hydroxylation imine initial intermediate involves isomerization ketone lipoamide mechanism methyl molecules monophosphate NAD+ Note nucleophilic nucleophilic addition O₂C occurs OH CH₂OPO32 OH H OH OH OH organic oxidation oxygen pathway phosphate protein proton pyruvate reaction reduction residue ribose ring SCOA serine shown in Figure step stereoisomers structure substrate synthase thioester tion transfer undergoes yield

Tietoja kirjailijasta (2005)

John E. McMurry received his B.A. from Harvard University and his Ph.D. at Columbia University. Dr. McMurry is a Fellow of the American Association for the Advancement of Science, and an Alfred P. Sloan Research Foundation Fellow. He has received several awards, which include the National Institutes of Health Career Development Award, the Alexander von Humboldt Senior Scientist Award, and the Max Planck Research Award. In addition to The Organic Chemistry of Biological Pathways, he is also the author of Organic Chemistry, Fundamentals of Organic Chemistry, and Chemistry (with Robert Fay).

Tadhg P. Begley received his B.Sc. from National University of Ireland and his Ph.D. at the California Institute of Technology. Dr. Begley is the recipient of many awards, including the Merck Faculty Development Award and the Camille and Henry Dreyfus Teacher-Scholar Award. His research group uses the principles and techniques of organic chemistry to study complex organic transformations found in vitamin biosynthetic pathways. In addition to The Organic Chemistry of Biological Pathways, Dr. Begley has edited Cofactor Biosynthesis: A Mechanistic Perspective.

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OtsikkoThe Organic Chemistry of Biological Pathways
KirjailijatJohn McMurry, Tadhg P. Begley, Tadhg P Begley
Painoskuvitettu
KustantajaRoberts and Company Publishers, 2005
ISBN0974707716, 9780974707716
Pituus490 sivua
  
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